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These findings are important because they clarify which kinds of MRI studies meet the "minimal-risk standard," which ethics review boards use to determine if a study can proceed.

The report appears in , a journal of The Hastings Center.

The side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria.

Tolerance and dependence will develop with continuous use, requiring increasing doses and leading to a withdrawal syndrome upon abrupt discontinuation.

The euphoria attracts recreational use, and frequent, escalating recreational use of opioids typically results in addiction.

An overdose or concurrent use with other depressant drugs commonly results in death from respiratory depression.

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